Six pro-Morsi demonstrators were killed when their rally came under fire in the canal city of Ismailia.
"We have six people, including a woman, shot with live ammunition," Ahmed al-Labban, director of a makeshift mobile field hospital, told Anadolu Agency.
"Four of them were dead on arrival and the other two are clinically dead," he added.
Seven people were killed in Ramses Square in downtown Cairo, the conversion point of multiple pro-democracy marches from areas throughout the capital.
Seven people were also killed in the Nile Delta city of Damietta in an attack by gunmen on a funeral for a pro-Morsi demonstrator killed earlier.
Unidentified gunmen also attacked a rally staged from Al-Rahma Mosque in Giza, leaving two injured.
A pro-Morsi rally in Giza Square also came under attack amid unconfirmed reports of at least one fatality.
Attackers also threw stones and Molotov cocktails at a demonstration in eastern Cairo's Ain Shams district.
Pro-democracy demonstrators were also attacked with teargas in the Nile Delta province of Daqahliya.
Pro-democracy demonstrators are staging a fresh wave of rallies in several Egyptian cities today to protest Wednesday's violent dispersal of their two main protest sites in Cairo and Giza.
"Our revolution is peaceful; we will continue to mobilize without violence or sabotage," the National Alliance for the Defense of Legitimacy, a pro-Morsi coalition of largely Islamist parties and figures, said in a Friday statement.
Egypt has been in a state of turmoil since security forces on Wednesday violently dispersed two major protest camps set up by pro-democracy demonstrators who condemnt the overthrow of country's first elected president Mohamed Morsi in Cairo's Rabaa al-Adawiya Square and Giza's Nahda Square.
The Health Ministry has said that at least 638 people had been killed in nationwide violence since Wednesday, including 288 in Rabaa and 87 in Nahda.
However, the official death toll remains far below that given by the pro-democracy alliance, which has put the number of deaths from the Rabaa sit-in alone at some 2,600.
